Precision medicine (PM) aims to revolutionise healthcare, but little is known about the role religion and spirituality might play in the ethical discourse about PM. This Perspective reports the outcomes of a knowledge exchange fora with religious authorities in Singapore about data sharing for PM. While the exchange did not identify any foundational religious objections to PM, ethical concerns were raised about the possibility for private industry to profiteer from social resources and the potential for genetic discrimination by private health (...) insurers. According to religious authorities in Singapore, sharing PM data with private industry will require a clear public benefit and robust data governance that incorporates principles of transparency, accountability and oversight. (shrink)

The intelligent transportation system under the big data environment is the development direction of the future transportation system. It effectively integrates advanced information technology, data communication transmission technology, electronic sensing technology, control technology, and computer technology and applies them to the entire ground transportation management system to establish a real-time, accurate, and efficient comprehensive transportation management system that works on a large scale and in all directions. Intelligent video analysis is an important part of smart transportation. In order to improve (...) the accuracy and time efficiency of video retrieval schemes and recognition schemes, this article firstly proposes a segmentation and key frame extraction method for video behavior recognition, using a multi-time scale dual-stream network to extract video features, improving the efficiency and efficiency of video behavior detection. On this basis, an improved algorithm for vehicle detection based on Faster R-CNN is proposed, and the Faster R-CNN network feature extraction layer is improved by using the principle of residual network, and a hole convolution is added to the network to filter out the redundant features of high-resolution video images to improve the problem of vehicle missed detection in the original algorithm. The experimental results show that the key frame extraction technology combined with the optimized Faster R-CNN algorithm model greatly improves the accuracy of detection and reduces the leakage. The detection rate is satisfactory. (shrink)

The intracellular multiprotein complex β‐catenin destruction complex plays a key role in Wnt/β‐catenin signaling. Wnt stimulation induces the assembly of the receptor‐associated signalosome and the inactivation of the destruction complex, leading to β‐catenin accumulation and transcriptional activation of the target genes. The core components of the destruction complex include Axin, APC, GSK3β, CK1α and other proteins. Recent studies demonstrated that Axin and APC undergo liquid–liquid phase separation (LLPS), which is critical for their function to regulate Wnt/β‐catenin signaling. Here, we discuss (...) the possible roles of LLPS in Wnt/β‐catenin signaling and regulation of Axin LLPS by post‐translational modifications. (shrink)

This study uses the Planned Risk Information Seeking Model (PRISM) to estimate the public's information seeking and avoidance intentions during the COVID-19 outbreak based on an online sample of 1031 Chinese adults and provides support for the applicability of PRISM framework in the situation of a novel high-level risk. The results indicate that information seeking is primarily directed by informational subjective norms (ISN) and perceived seeking control (PSC), while the main predictors of information avoidance include ISN and attitude toward seeking. (...) Because ISN are the strongest predictor of both information seeking and avoidance, the way the public copes with COVID-19 information may be strongly affected by individuals' social environment. Furthermore, a significant relationship between risk perception and affective risk response is identified. Our results also indicate that people who perceive greater knowledge of COVID-19 are more likely to report greater knowledge insufficiency, which results in less information avoidance. (shrink)

Ben shu jie shao le gong zi zhen, wei yuan, yan fu, kang you wei, tan si tong, liang qi chao, chen tian hua, zhang bing lin deng wan qing si xiang jia de zhe xue si xiang.

本书的内容包括:现代性与时间、心体与审美、审美共通感的社会认同功能:审美时尚在当代中国转型期的政治哲学涵义等.

倫理是人與人之間的生存法則，也是建立人類社會秩序的基礎。《大英百科全書》有言：「倫理學的同義詞是道德哲學。」可知倫理與道德為一體之兩面。 本書以提綱挈領的方式，講述東西方倫理觀的軌跡、傳承與差異。說理明析，條目清楚，更深入探討倫理道德之重要性，試圖喚醒人們心靈中純正光明之善意，並重視生命內在底蘊的培育積累。 作者游芳憫為海內外備受敬重之儒學專家，廣閱群書，對哲學、史學、神學、社會學等領域均有精深研究，更進而行旅天下，實地觀察世界各方風土民情，本書為其多年研究及講學之學術資料，讀者閱後必能對中西倫理學有一番 全面而系統的認識，是極具研讀價值的入門參考書。【秀威資訊科技股份有限公司製作】.

本书试图重新将《说儒》放置在近现代的政治现实和学术史的大语境中考察，从日记、书信、文章著作中挖掘史料并进行再评估，探究胡适对儒学认识的变化轨迹，解释其在20世纪三四十年代抗战酝酿到爆发过程中所持立场与 其思想根源的关系。.

Tian dao guan shi Zhongguo zhe xue de zhong yao gai nian, ye shi ru jiao de yi ge zhong yao wen ti, ji, shen me shi tian dao? Qi jin wei zhi, ji hu suo you de Zhongguo zhe xue zhu zuo, dou ren wei tian dao jiu shi zi ran gui lü. Ben shu jiang tong guo wen xian zi liao xiang dang dai de du zhe shuo ming, Zhongguo gu dai de tian dao, jiu shi tian zhi (...) dao, shang tian zhi dao. (shrink)

Pierre-Joseph Proudhon was a nineteenth-century French philosopher and socialist whose contributions played an integral role in anarchist and socialist thought. This book offers an in-depth analysis of Proudhon's political theories, including his ideas about property, labor relations, and the state. Through a close reading of primary sources, the author provides a nuanced and engaging account of Proudhon's contributions to political thought. This book is a valuable resource for scholars and anyone interested in the history of anarchist and socialist thought. This (...) work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Ben shu wei "Song Ming shi qi Chang Jiang zhong you de ru xue yan jiu" cong shu zhi yi: ben cong shu shi ren wen she hui ke xue chong dian yan jiu ji di-Wuhan da xue Zhongguo chuan tong wen hua yan jiu zhong xin tou biao, jing jiao yu bu zu zhi zhuan jia ping shen tong guo, zheng shi pi zhun de jiao yu bu ren wen she hui ke xue 2001 nian du zhong da yan (...) jiu xiang mu, xiang mu pi zhun hao shi 01JAZJD720008, ding yu 2004 nian qian hou wan cheng. ke ti zu zhu chi ren wei Guo Qiyong jiao shou, "Jiangxi zhi xue"shi Zhu Xi ti chu de yi ge gai nian, zhu yao zhi chu zi yu Jiangxi Jinxi Lu shi jia zu yi men de xue shuo, qi nei he shi Lu Jiuyuan de xin xue; di 2 quan ze shi you "Song Yuan xue an" suo zai zhi Xiangshan xiong Zhangfu, Suoshan de xue shuo; di 3 quan wei Xiangshan xiong di de di zi men de si xiang. Ben shu quan mian kao cha Jiangxi zhi xue zai Song dai Chang Jiang zhong you xing qi de xue mo yuan yuan, zhu yao xue shuo, yu Luo xue Min xue Zhejiang zhu xue zhe (Lü Zuqian, Yong Shangsi xian sheng deng) zhi jian de guan xi, yi ji qi dui Wang (Yangming) xue xing qi de nei zai guan lian xing, bing yan ji dui xian dai xin ru xue de tan tao. ben shu de xie zuo jiang zhu zhong si xiang kao gu de fang fa, zai quan mian yan jiu you guan dian ji de ji chu shang, dui you guan ren wu de chu sheng di, huo dong de di qu (ru jia zu suo zai cun luo, xue zhe shu xin wang lai, jiang xue, hui jiang, shu yuan deng) jin xing shi di de kao cha, guang fan di yun yong fang zhi, nian pu, shu yuan zhi, jia pu deng cai liao, ba si xiang jia huan yuan yu ju ti huan jing zhi zhong, zai ju ti she hui de li shi de jia zu de bei jing xia kao cha qi si xiang de nei han, jie shi qi jing shen suo zai, bing jin er yin shen chu qi yi yi yu jia zhi. (shrink)

Chuan bo Zhuzi jia li, xuan jiang Tai zu sheng yu, shi Ming chao zai di fang tui xing de zui zhu yao de liang zhong she hui li jiao xing shi, xian shi chu li zhi shi zhong shi wang chao zheng zhi de yi ge he xin li nian he shou dao te bie qiang diao de she hui zhi li fang shi. Jia li shi wang chao zheng zhi wen hua de yi bu fen, Ming chao wei (...) le tui guang jia li, jian li qi duo qu dao, duo ceng ji de jia li chuan bo: ji you guan fang chang dao ye you min jian zi wei, ji you li shu, li tu deng wen ben xing shi, yi you shi ren shi fan, zhi dao deng fei wen ben xing shi. (shrink)

Detailed summary in vernacular field only.

本书采用类似于古希腊与先秦时代的对话体灵思形式与后现代主义的大面积思片播撒方式,通过对十三位目前在国内边缘思想与先锋艺术等领域颇具代表性与影响力的人物的思想追问,展示了世界文化的多维空间景观及其人文精 神。.

本书将马克思主义与科学社会主义置于“当代诠释学的视野”加以解读、追问和探寻,试图在新时代地平线上构建一个当代诠释学与马克思主义相融通的视域。.